Antibodies to coronavirus in men decrease faster than in women

Antibodies to coronavirus in men decrease faster than in women

A group of scientists from France analyzed blood samples of several hundred patients who had been ill for six months and made an amazing discovery: the level of antibodies in men decreases significantly faster than in women. This discovery may change the approach to coronavirus vaccination, which starts in different countries of the world next year.

Scientists from the Institut Pasteur have been monitoring the dynamics of immunity against coronavirus for six months in 308 employees of hospitals of the University of Strasbourg (University of Strasbourg), in whom COVID-19 was confirmed. Most of the patients in this sample had a mild form of the disease.

The researchers tested the participants’ antibody levels using three different tests twice over a period of 172 days. The highest level at the first analysis was detected in blood samples of men over 50 years of age and overweight patients. Upon repeated analysis, the scientists found that in men, the level of antibodies, including neutralizing proteins, decreased significantly more than in women, regardless of age and weight.

Scientists have noted that in the acute phase of the disease, the antibody titer in men is higher, but decreases much faster, while in women it remains fairly stable. Researchers cannot yet find an explanation for this phenomenon, but they assume that the dynamics of the decrease in antibodies directly depends on their level in the acute phase.

This is the first study to compare and analyze the production of antibodies in men and women, and it may have an impact on the approach to the upcoming vaccination against COVID-19. It is possible that men will need an additional dose of the drug to form a stable immunity, according to experts from the website about men’s health . At the moment, the work of scientists at the Pasteur Institute has not yet been peer-reviewed and published in the form of a preprint.

that the majority of participants had antibodies persisted for the first six months with a tendency to decrease in concentration. The number of T cells decreased slowly, while the number of B lymphocytes only increased over time, and this was a great discovery for scientists. According to scientists, this suggests that immunity to coronavirus can last for years, reliably protecting against re-infection of the pathogen. If these data are confirmed, there may be no need for annual vaccination against SARS-Cov-2.