This year witnessed a number of scientific breakthroughs with consequences that changed the world.
NASA launched Parker Solar Probe to conduct unprecedented solar research, while in October healthy mice were born with two genetic mothers.
More controversially, Chinese scientist He Jiankui caused a shock wave in November when he claimed to have succeeded in modifying the genes of twin girls so that they could not catch HIV.
However, his research has not been verified by others.
It is impossible to say exactly what will be saved in 2019 but below are a number of predictions and possible events that can prove a breakthrough.
Genetically modified superhores will be born
It was revealed at the end of December 2017 that scientists in Argentina had succeeded in rewriting the cloned horse genome.
The foals will be born this year and are said to be faster, stronger, and better to jump than their usual counterparts.
The team used a technique called Crispr to edit DNA and had planned to implant healthy embryos in surrogate mothers within two years.
We can see what the black hole looks like for the first time
You might assume that because you have heard a lot about black holes, we might have seen it.
But the reality is that scientists have never managed to describe it, until next year.
The Event Horizon Telescope (EHT) has made its first observation about supermassive black holes at the center of our galaxy.
According to New Scientist, that observation could include the first picture.
SpaceX can be launched using NASA astronauts
SpaceX's capsule Crew Dragon has been developed as a replacement for NASA's space shuttle to transport up to seven astronauts to the International Space Station.
If the flight test was successful in January, the flight test with the astronauts will take place at the end of the year.
Next month's test will see SpaceX Falcon 9 rockets carrying capsules before anchoring with the space station and returning to earth.
Can we see the arrival of universal flu shots?
Science News Writer Aimee Cunningham speculates whether 2019 can see the arrival of the first universal flu vaccine.
It was reported last month how such developments have entered the Phase 3 trial phase ahead of winter.
The shot means that the vaccine that protects from the previous year will not be worn out.
This has the potential to protect against seasonal flu for years or a pandemic outbreak.
According to The Scientist, it will take 20 years to reach this stage so that any solution in the near future remains to be seen.
An exploration of new dawn on the moon
2018 can end with the landing of a Chinese landing craft on the dark side of the moon – this will be the first soft landing on the far side of the moon's body.
But this nation has ambitions to pursue the US and Russia as the main space forces by 2030 and the current mission does not represent the only effort to go to next month.
Another craft, which seems to be launched in 2019, will bring the first moonstone back to the moon since 1976.
The two missions are the beginning of renewed interest in trying to reach the lunar surface with the US which aims to make astronauts land in the late 2020s.