Enterobacter bugandensis exists as a nosocomial pathogen (hospital) and can cause life-threatening infections in neonates and immunocompromised patients. In particular it has been associated with association with neonatal sepsis. With Enterobacter species in general, the urinary tract and respiratory tract are the most common sites of infection.
What is also of concern, as reported by BioExpert, is that isolated species have the potential to lead to health considerations that are important for future missions. This is still potential, because it is not known what the effect of microgravity on pathogenicity. bacteria like that. In terms of origin, it is not surprising that the genomes of five ISS Enterobacter strains are genetically similar to the three strains found on Earth.
However, as reported by the Daily Mail Dr. Nitin Singh, lead author of the report, said: "Given the results of multi-drug resistance for this [bacteria] and the increased likelihood of pathogenicity that we have identified, this species has the potential to give rise to health considerations that are important for future missions. "
In terms of potential pathogenicity for humans, the PathogenFinder algorithm shows there is a possibility that more than 79 percent of the organisms that cause infection if they enter the bloodstream. PathogenFinder is a web-server for predicting the pathogenicity of bacteria by analyzing proteome inputs (a whole set of proteins that, or can, be expressed by an organism at a certain time), genomes, or raw readings provided by users.
The new findings, which highlight how humans can pollute the places they visit, have been published in the journal BMC Microbiology, with the title "Multi-drug medicine Enterobacter bugandensis species isolated from the International Space Station and comparative genome analysis with human pathogenic strains. "