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Broccoli compounds can stop the development of cancer tumors



Mexico, May 17 (Notimex). – A group of international researchers found that compounds in broccoli and Brussels sprouts were able to block cancer tumors.

Pier Paolo Pandolfi, a Medical and Pathology academic at Harvard Medical School and research leader, identified a compound called I3C, which develops in the body and prevents tumors from developing.

According to information from educational institutions, the work is based on the function of a cancer suppressor gene called PTEN, one of the most important tumor suppressors in the history of the disease.

According to Harvard University, this gene is usually attacked by cancer, which tries to eliminate, mutate, or deactivate it.

Specialists, who use human cells and mice to develop prostate cancer, found that an enzyme called WWP1 that promotes cancer growth is very important to disrupt the PTEN function.

The study, published in the journal "Science", could enable the development of drugs based on WWP1 suppression and PTEN release to achieve results.

It can also help people with genetic deficiencies from PTEN that make them vulnerable to cancer, and cause developmental disabilities that can cause intellectual disability or mental illness.

"We believe that this class of drugs can be very important for human health beyond cancer," said Pandolfi.

PTEN protective compounds, I3C, are found in cross vegetables such as broccoli, Brussels sprouts, cabbage and cauliflower.

Specialists emphasize that it is also necessary to carry out additional analysis to study the appropriate dosages and unwanted effects of I3C supplements.

This work was developed at the Cancer Center and Cancer Research Institute of Beth Israel Deaconess Medical Center by Pandolfi and his team, representatives from institutions in the United States, Taiwan, China, Italy, Australia and India and supported by the National Institutes of Health.

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