More than a third, 35%, of Britons say they are unlikely to use a COVID-19 vaccine, according to a new poll released on Sunday.
The poll was conducted by the newspaper Opinium for the Observer, and also found that 48% of Brits fear it will not be safe, and 47% fear it will not be effective.
More than half, 55%, said they feared it would have side effects.
However, only 20% said they would not be likely to use a vaccine when it was available if the government recommended them to take it, to which less than 24% responded two weeks ago.
Overall, 68% said they would pick them up when they were available and the government recommended they do, up from 67% two weeks ago.
The UK Health Department says the vaccine will be deployed from next Tuesday.
The first batch of Pfizer-BioNTech vaccine arrived last Thursday, and about 800,000 doses will be available in the UK from next week.
The government has ordered 40 million doses of the vaccine, enough for 20 million people to be given two doses every 21 separate days.
The government has also announced the order in which people will be vaccinated.
The first are nursing home residents and their caregivers, followed by more than 80s and frontline health and social care workers.
Then over 75, followed by over 70s and those who were clinically very vulnerable, then over 65, then those aged 16 to 64 with underlying health conditions.
These groups will be followed by the over 60s, then-over-55, and then-above-50s.
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